Covid latest: Cholesterol is the key factor for severe covid infections says latest study
The novel coronavirus has been known to affect people in a number of different ways with some experiencing a severe infection and others not. Now, a recent study suggests the amount of cholesterol a person is carrying may be the key factor into the severity of COVID-19 infection.
“We find that the S1 subunit of SARS-2-S binds to cholesterol and possibly to HDL components to enhance viral uptake in vitro.
“Our findings reveal that B type 1 acts as a host factor that promotes SARS-CoV-2 entry and may help explain viral tropism, identify a possible molecular connection between COVID-19 and lipoprotein metabolism, and highlight B type 1 as a potential therapeutic target to interfere with SARS-CoV-2 infection.
“B type 1 is a cell-surface HDL receptor that mediates the selective uptake of cholesteryl esters and other lipid components of receptor-bound HDL particle.”
