The Best Drama and Comedy-Drama Series on Amazon Prime Video

What are the best drama and comedy-drama TV series on Amazon Prime Video? The 13 titles below star actors such as Sterling K. Brown, Hugh Grant, Hugh Laurie, Hugh Bonneville, Ben Whishaw, Elizabeth McGovern, Rosa Salazar, Jay Duplass, William H. Macy, Emmy Rossum, Lola Kirke, Gael García Bernal, Christine Baranski, Dominic West, Ruth Wilson, and Shweta Tripathi. And they come from the minds of Ava DuVernay, Russell T Davies, Raphael Bob-Waksberg, Kate Purdy, Robert and Michelle King, Joey Soloway, Dan Fogelman, Paul Abbott, David Shore, Julian Fellowes, Sarah Treem, Biswa Kalyan Rath, and Shankar Nag.
You might find more drama and comedy-drama TV shows in our list of best TV series.
The Best TV Series on Amazon Prime Video
- The Affair (2014 – 2019)
A schoolteacher and budding novelist (Dominic West) begins an extramarital affair with a young waitress (Ruth Wilson) trying to piece together her life in this sombre drama, which delivered two strong seasons of deep and psychological observation before a slight dip brought by plot struggles in the third season. Recovered marginally for fifth and final season.
- Downton Abbey (2010 – 2015)
A post-Edwardian era period drama set in the English countryside, dealing with the aristocratic Crawley family and their domestic servants, and how the great events of the 1910s and 1920s had an effect on their lives and the British social hierarchy. Went through a dip in quality in the middle to late years but recovered for the final season. The follow-up 2019 movie is on Apple TV and Google Play.
- The Good Fight (2017 – Present)
A spin-off sequel to the critically-acclaimed The Good Wife follows Diane Lockhart (Christine Baranski) after she’s forced out of the law firm where she was a partner, and has to join a high-profile law firm in Chicago. The legal/political drama has more than held its own unlike most spin-offs, and has been praised for its examination of topical social issues.
For eight long years, Hugh Laurie played the misanthropic and unconventional titular doctor who despite reliance on pain medication and a cane — it actually added to his acerbic personality — led a team at a fictional New Jersey hospital, and made great use of his out-of-the-box thinking and instincts to diagnose patients.
Biswa Kalyan Rath’s anthology series offers a look at unfortunate souls — a teenager stuck at an engineering coaching institute, or a young doctor posted to a rural cataract camp — fighting against prejudices, the system, and more. And generally failing. Exclusive to Amazon.


